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Biol Bull 113: 296-301. (October 1957)
© 1957 Marine Biological Laboratory
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ISOLATION AND ASSAY OF THE NEMATOCYST TOXIN OF METRIDIUM SENILE FIMBRIATUM

JOHN H. PHILLIPS JR. 1 and DONALD P. ABBOTT 1

1 Hopkins Marine Station of Stanford University, Pacific Grove, California

1. A method of obtaining purified suspensions of nematocysts has been developed, and a method of obtaining the toxin they contain has been described.

2. A method of assay, using inhibition of the righting response of Littorina planaxis, has been shown to be applicable for toxicity titrations.

3. Further work on the chemical and immunochemical characterization of the toxin is planned, as well as the use of the toxin for studies of antitoxic immunity in marine invertebrates.






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Copyright © 1957 by the Marine Biological Laboratory.