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1 Biology Department, The Catholic University of America, Washington, D. C.
1. The mesonephroi from 63 Rana sylvatica tadpoles and young adults were studied in sectioned material by means of a caryometric method for determination of nuclear volumes. Frequency histograms drawn from the data reveal three peak classes which, when arranged in series, give the progression, 1:1.5:2. These results are interpreted as being due to an interphasic growth preceding mitosis.
2. The results are discussed in terms of morphological increase and decrease in nuclear size, increase and decrease of DNA values, polyploidy, the "constancy" hypothesis, physiological activity and histological differentiation.
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