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Biol Bull 118: 66-69. (February 1960)
© 1960 Marine Biological Laboratory
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THE EFFECTS OF THYROXIN AND GROWTH HORMONE ON LIVER POLYPLOIDY

I. I. GESCHWIND 1, M. ALFERT 1, and C. SCHOOLEY 1

1 Hormone Research Laboratory, and Department of Zoology and its Cancer Research Genetics Laboratory, University of California, Berkeley 4, California

1. The effect of thyroxin and of growth hormone on liver polyploidy has been investigated in the dwarf mouse and in the hypophysectomized rat.

2. Either hormone, acting alone, stimulated polyploidization in these experimental animals; the combination of both hormones synergized to produce an hepatic cell picture dominated by higher polyploid classes.






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Copyright © 1960 by the Marine Biological Laboratory.