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1 Department of Zoology and Comparative Physiology, University of Birmingham, Birmingham, England
2 Department of Biology, Stanford University, Stanford, California 94305
Hypophysectomized Fundulus in fresh water lost sodium several times as rapidly as normal fish. The greater part of the loss takes place extrarenally. Prolactin reduces the loss almost to normal levels, thus prolonging survival. The possible functions of prolactin in osmoregulation in normal fish are discussed.
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