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1 Department of Zoology and Physiology , Louisiana State University, Baton Rouge, Louisiana 70803
Injections of prolactin late during a 16-hour daily photoperiod are more effective in promoting the red eft water drive than are injections of prolactin given early or at midday. The daily variation in the water drive response to prolactin appears to be phased by the photoperiod and mediated by the interrenal system. The time of corticosterone injection sets the daily rhythm of water drive responsiveness to prolactin. Prolactin is most effective at 8 hours following corticosterone, and least effective about 16 hours after corticosterone.
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