Biol. Bull. Sign up for etocs!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Biol Bull 164: 41-49. (February 1983)
© 1983 Marine Biological Laboratory
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CHAIN, B. M.
Right arrow Articles by ANDERSON, R. S.
Right arrow Search for Related Content
PubMed
Right arrow Articles by CHAIN, B. M.
Right arrow Articles by ANDERSON, R. S.

ANTIBACTERIAL ACTIVITY OF THE COELOMIC FLUID FROM THE POLYCHAETE, GLYCERA DIBRANCHIATA. II. PARTIAL PURIFICATION AND BIOCHEMICAL CHARACTERIZATION OF THE ACTIVE FACTOR

BENJAMIN M. CHAIN 1 and ROBERT S. ANDERSON 1

1 Sloan-Kettering Institute for Cancer Research, Donald S. Walker Laboratory, 145 Boston Post Rd., Rye. New York 10580

The coelomic fluid of Glycera dibranchiata is bactericidal for the Gram-negative rod, Serratia marcescens. An active factor has been partially purified using gel chromatography and affinity chromatography on concanavalin A-Sepharose, and has been shown to be a glycoprotein with a molecular weight of 2.5-4.5 x 105 containing bound divalent cations and at least one disulfide bridge. The active molecule showed no biochemical similarities to other humoral bactericidal systems, either vertebrate or invertebrate, and would appear to define a new class of antibacterial molecules.

Submitted on May 10, 1982
Accepted on October 8, 1982






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1983 by the Marine Biological Laboratory.