Biol. Bull. Sign up for etocs!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Biol Bull 176: 140-144. (April 1989)
© 1989 Marine Biological Laboratory
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MCCAIG, C. D.
Right arrow Articles by DOVER, P. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MCCAIG, C. D.
Right arrow Articles by DOVER, P. J.

On the Mechanism of Oriented Myoblast Differentiation in an Applied Electric Field

COLIN D. MCCAIG 1 and PHILIPPA J. DOVER 1

1 Department of Physiology, Marischal College, University of Aberdeen, Aberdeen AB9 1AS, Scotland

We are investigating the mechanism of perpendicular differentiation of myoblasts in an applied electric field. Electric fields have latent effects in this regard. Perpendicular alignment can occur at least an hour after the field has been switched off. Polarization of the axis of development was a Ca++-dependent process, being blocked by Co++ and mimicked by a unilateral source of the calcium channel agonist Bay K8644. Surprisingly, several types of organelles became distributed asymmetrically within the cytoplasm of oriented and orienting cells. Whether these asymmetries underpin orientation, together with the explanation for organelle asymmetry, are unclear.




This article has been cited by other articles:


Home page
 J. Cell Sci.Home page
M. E. Mycielska and M. B. A. Djamgoz
Cellular mechanisms of direct-current electric field effects: galvanotaxis and metastatic disease
J. Cell Sci., May 1, 2004; 117(9): 1631 - 1639.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the Marine Biological Laboratory.