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The Biological Bulletin, Vol 183, Issue 1 178-184, Copyright © 1992 by Marine Biological Laboratory
SIGNALING SYSTEMS, VENOMS, AND ADHESIVES: RECURRING THEMES AND VARIATIONS |
J. H. Waite
Marine Biology-Biochemistry Program, College of Marine Studies, University of Delaware, Lewes, Delaware 19958
3,4-Dihydroxyphenylalanine (DOPA) occurs transiently in nature as a free or peptide-bound amino acid. It is probably universally distributed in tissues and fluids of invertebrates. DOPA is a highly versatile metabolite, participating in neuroendocrine, immune, and reproductive functions, as well as in the formation of such products as bioadhesives, silks, integuments, and pigments. The mechanism by which DOPA is formed from tyrosine or peptidyl tyrosine remains to be determined in most cases. Future advances in DOPA chemistry may lead to a better understanding of the resonance between structural and sensory functions in animals.
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