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Biol Bull 81: 163-167. (October 1941)
© 1941 Marine Biological Laboratory
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THE RESPONSES OF CATFISH MELANOPHORES TO ERGOTAMINE

G. H. PARKER 1

1 From the Biological Laboratories, Harvard University

1. Ergotamine acts on only innervated melanophores by inducing them to disperse their pigment. It is without effect on denervated melanophores either with dispersed or with concentrated pigment.

2. It acts on innervated melanophores only indirectly, that is, through their nerves. These are excited by ergotamine centrally to produce at their melanophore terminals acetylcholine which causes the color cells to disperse their pigment.

3. Ergotamine is a good example of an indirect excitant of melanophores as contrasted with direct excitants such as intermedine, acetylcholine, and adrenaline, all of which act directly on these color cells.






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Copyright © 1941 by the Marine Biological Laboratory.