Biol. Bull. Sign up for etocs!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Biol Bull 94: 267-274. (June 1948)
© 1948 Marine Biological Laboratory
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by BARRON, E. S. G.
Right arrow Articles by NARAHARA, H. T.
Right arrow Search for Related Content
PubMed
Right arrow Articles by BARRON, E. S. G.
Right arrow Articles by NARAHARA, H. T.

THE EFFECT OF NITROGEN MUSTARDS ON THE RESPIRATION AND FERTILIZATION OF SEA URCHIN SPERM AND EGGS

E. S. GUZMAN BARRON 1, J. E. SEEGMILLER 1, E. G. MENDES 1, and H. T. NARAHARA 1

1 Chemical Division, Department of Medicine, The University of Chicago, and the Marine Biological Laboratory, Woods Hole

The halogenated alkyl amines, methyl bis (beta-chloroethyl) amine HCl, isopropyl bis (beta-chloroethyl) amine HCl, ethyl bis (beta-chloroethyl) amine HCl, and tris (beta-chloroethyl) amine HCl, when added to sperm suspensions of Arabacia punctulata increased their respiration. This increase seems to affect the entire respiratory process as shown by the unaltered R.Q. value. Anaerobic glycolysis was not altered. With dilute sperm suspensions (1:200) the stimulation pf respiration was followed by inhibition. Sperm so treated produced, on fertilization of eggs, an inhibition in the rate of cleavage, of pluteus formation, and motility of blastula, and produced in addition a number of malformations.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1948 by the Marine Biological Laboratory.